Specificity
Mouse anti Human Glial Fibrillary Acidic Protein antibody, clone GF-05 recognizes humanm glial fibrillary acidic protein (GFAP). GFAP is a 432 amino acid intermediate filament protein. Mouse anti Human Glial Fibrillary Acidic Protein antibody, clone GF-05 recognisez ~38-45 kDa neurofilaments in immunoblots. Mouse anti Human Glial Fibrillary Acidic Protein antibody, clone GF-05 is also reactive in ELISA with antigen coating at 5 μg/ml and may react with GFAP from other species.Mutations in the GFAP gene may result in presentation of Alexander disease (ALXDRD), a rare neurological condition affecting infants and characterized by myelination failure leading to early death (Brenner et al. 2001)