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Anti-GSK3 alpha (phospho Ser21) Antibody (A283623)

This product is discontinued

Anti-GSK3 alpha (phospho Ser21) Antibody (A283623) has been discontinued and is no longer available.

View all GSK3 alpha Antibodies.

Name
Anti-GSK3 alpha (phospho Ser21) Antibody
Description
Rabbit polyclonal antibody to GSK3 alpha (phospho Ser21).
Specificity
This antibody recognises GSK3 alpha when phosphorylated at serine 21. GSK3 is a member of the CMGC family of kinases. GSK3 comprises two isoforms, alpha and beta, with 85% total homology and 98% homology between kinase domains. GSK3 alpha is phosphorylated at serine 21 by protein kinase A, AKT and ribosomal S6 kinases p90RSK and p70S6K. Phosphorylation of GSK3 alpha at serine 21 leads to inactivation of GSK3 alpha.
Applications
WB
Dilutions
WB: 1:500 - 1:2,000
Reactivity
Human
Immunogen
Phospho-specific peptide corresponding to residues surrounding Ser21 of human GSK3 ALPHA.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
Lot Specific
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti GSK3 Alpha (pSer21) antibody recognizes GSK3 alpha when phosphorylated at serine 21. GSK3 is a member of the CMGC family of kinases. GSK3 comprises two isoforms, alpha and beta, with 85% total homology and 98% homology between kinase domains. GSK3 alpha is phosphorylated at serine 21 by protein kinase A, AKT and ribosomal S6 kinases p90RSK and p70S6K. Phosphorylation of GSK3 alpha at serine 21 leads to inactivation of GSK3 alpha.
Synonyms
EC:2.7.11.1, Glycogen synthase kinase-3 alpha, GSK-3 alpha, GSK3A, Serine/threonine-protein kinase GSK3A
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.

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