Anti-H-FABP Antibody [10E1] (A278771)

Anti-H-FABP Antibody [10E1]

Mouse monoclonal [10E1] antibody to H-FABP.

This antibody recognises human H-FABP, also known as heart type fatty-acid binding protein, and FABP3. H-FABP belongs to the FABP family, and is a 14kDa cytosolic non-enzymatic protein involved in the uptake, transport and metabolism of fatty acids. H-FABP also has a role in cell proliferation and is a candidate tumour suppressor gene in breast cancer. H-FABP was initially purified from the heart muscle, but has since been found to have a widespread tissue distribution, with highest concentration in cardiac and skeletal muscle. H-FABP has been implicated in neurodegenerative disorders, including Down syndrome and Alzheimer’s disease, and is a specific and sensitive biomarker for acute myocardial infarctions.

ELISA, Immunoassay

Human

Human heart FABP (H-FABP).

Mouse

Monoclonal

10E1

IgG1

Protein A affinity chromatography of ascites.

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human H-FABP antibody, clone 10E1 detects human H-FABP, also known as heart type fatty-acid binding protein, and FABP3. H-FABP belongs to the FABP family, and is a 14kDa cytosolic non-enzymatic protein involved in the uptake, transport and metabolism of fatty acids. H-FABP also has a role in cell proliferation and is a candidate tumour suppressor gene in breast cancer. H-FABP was initially purified from the heart muscle, but has since been found to have a widespread tissue distribution, with highest concentration in cardiac and skeletal muscle. H-FABP has been implicated in neurodegenerative disorders, including Down syndrome and Alzheimer’s disease, and is a specific and sensitive biomarker for acute myocardial infarctions.

FABP11, Fatty acid-binding protein 3, Fatty acid-binding protein, heart, Heart-type fatty acid-binding protein, M-FABP, Mammary-derived growth inhibitor, MDGI, Muscle fatty acid-binding protein