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Anti-IL-1 alpha Antibody - BSA and Azide free (A283762)

This product is discontinued

Anti-IL-1 alpha Antibody - BSA and Azide free (A283762) has been discontinued and is no longer available.

View all IL-1 alpha Antibodies.

Name
Anti-IL-1 alpha Antibody - BSA and Azide free
Description
Rabbit polyclonal antibody to IL-1 alpha.
Specificity
This antibody recognises human IL-1 alpha (Interleukin-1 alpha), an 18kDa multi-functional pro-inflammatory cytokine which belongs to the IL-1 family of proteins, and is produced by a variety of cells including activated macrophages, monocytes and keratinocytes.IL-1 alpha and IL-1 beta have been identified as two distinct IL-1 proteins which bind to the same type 1 Interleukin 1 receptor (IL1R1). Biological properties of IL-1 alpha include stimulation of thymocyte proliferation by induction of IL-2 release, B-cell proliferation and maturation, and fibroblast growth factor activity.
Applications
WB, ELISA, IHC-P, Functional Assays
Dilutions
ELISA: 0.5 µg/ml, Functional Assays: 1.0 - 2 µg/ml, WB: 0.1 - 0.2 µg/ml
Reactivity
Human
Immunogen
Recombinant human IL-1alpha.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
1 mg/ml after reconstitution.
Product Form
Lyophilized
Reconstitution
Reconstitute with 0.1 ml of distilled water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide.
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti Human Interleukin-1 alpha antibody recognizes human IL-1 alpha (Interleukin-1 alpha), an 18kDa multi-functional pro-inflammatory cytokine which belongs to the IL-1 family of proteins, and is produced by a variety of cells including activated macrophages, monocytes and keratinocytes.IL-1 alpha and IL-1 beta have been identified as two distinct IL-1 proteins which bind to the same type 1 Interleukin 1 receptor (IL1R1). Biological properties of IL-1 alpha include stimulation of thymocyte proliferation by induction of IL-2 release, B-cell proliferation and maturation, and fibroblast growth factor activity.
Synonyms
Hematopoietin-1, IL1A, IL1F1, Interleukin-1 alpha
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.

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