This antibody recognizes a common extracellular epitope on MICA and MICB glycoproteins, transmembrane ligands of NKG2D, and is able to block NKG2D-mediated activation of NK cells and cytotoxic T cells.
Applications
Flow Cytometry, IP, IHC
Dilutions
Flow Cytometry: 1-4 µg/ml.
Reactivity
Human
Immunogen
Transfected C1R cells expressing MICA.
Host
Mouse
Clonality
Monoclonal
Clone ID
6D4
Isotype
IgG2a
Conjugate
Unconjugated
Purification
Protein A chromatography.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline, pH 7.4, with 15 mM Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.
Synonyms
MHC class I chain-related protein A, MHC class I chain-related protein B, MHC class I polypeptide related sequence A, MHC class I polypeptide related sequence B, MHC class I polypeptide-related sequence A, MIC-A, micA, MICA_HUMAN, MICB
Human monoclonal antibody to MICA + MICB Research grade Anti-Human MICA + B [7C6] biosimilar for ELISA, Flow Cytometry, Functional Studies and in vivo Research.
Human monoclonal antibody to MICA + MICB Research grade Anti-Human MICA + B [7C6] biosimilar for ELISA, Flow Cytometry, Functional Studies and in vivo Research.
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