Anti-STAT6 (phospho Tyr641) Antibody (A283684)

Anti-STAT6 (phospho Tyr641) Antibody

Rabbit polyclonal antibody to STAT6 (phospho Tyr641).

This antibody recognises STAT6, also known as IL-4 Stat when phosphorylated at tyrosine 641. STAT6 is a member of the STAT family of transcription factors. STATs reside in the cytosol until activated. Upon activation STATs dimerize and translocate to the nucleus where they exert their transcriptional effects. STAT6 is phosphorylated at tyrosine 641 by Janus associated kinases (JAKs) leading to dimerization and relocation to the nucleus.

WB, IHC-P

IHC-P: 1:50 - 1:100, WB: 1:500 - 1:2,000

Human

Phospho-specific peptide corresponding to residues surrounding Tyr641 of human STAT6.

Rabbit

Polyclonal

IgG

Lot Specific

Liquid

Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti STAT6 (pTyr641) antibody recognizes STAT6, also known as IL-4 Stat when phosphorylated at tyrosine 641. STAT6 is a member of the STAT family of transcription factors. STATs reside in the cytosol until activated. Upon activation STATs dimerize and translocate to the nucleus where they exert their transcriptional effects. STAT6 is phosphorylated at tyrosine 641 by Janus associated kinases (JAKs) leading to dimerization and relocation to the nucleus (Wurster et al. 2000).

IL-4 Stat, Signal transducer and activator of transcription 6