Anti-VEGFA Antibody [CD17-1E1] (A280083)

Anti-VEGFA Antibody [CD17-1E1]

Mouse monoclonal [CD17-1E1] antibody to VEGFA.

This antibody recognises vascular endothelial growth factor alpha (VEGF-A) which forms a homodimer and is a potent stimulator of angiogenesis of both normal and cancerous cells. It acts as a regulator of vasculogenesis, angiogenesis and endothelial cell growth. VEGF-A is secreted by many different cell types such as endothelial cells , smooth muscle cells , neutrophils , platelets , macrophages and 60% of all tumors. The purified Mouse anti Human VEGF antibody, clone CD17-1E1 (MCA6286GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human VEGF antibody, clone CD19-4G11 (MCA6287B) as the detection antibody.

ELISA: 1 µg/ml

Human

E. coli derived recombinant full length human VEGF (Ala27-Arg147).

Mouse

Monoclonal

CD17-1E1

IgG2b

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human VEGF antibody, clone CD17-1E1, recognizes vascular endothelial growth factor alpha (VEGF-A) which forms a homodimer and is a potent stimulator of angiogenesis of both normal and cancerous cells. It acts as a regulator of vasculogenesis, angiogenesis and endothelial cell growth. VEGF-A is secreted by many different cell types such as endothelial cells (Nissen et al. 1998), smooth muscle cells (Brogi et al. 1994), neutrophils (Gaudry et al. 1997), platelets (Banks et al. 1998), macrophages and 60% of all tumors (Berse et al. 1992). The purified Mouse anti Human VEGF antibody, clone CD17-1E1 (MCA6286GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human VEGF antibody, clone CD19-4G11 (MCA6287B) as the detection antibody.

L-VEGF, Vascular endothelial growth factor A, long form, Vascular permeability factor, VEGF, VPF