Anti-CD34 Antibody [QBEnd/10] - BSA and Azide free (A253857)

Mouse monoclonal [QBEnd/10] antibody to CD34 for Flow Cytometry, IF and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

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Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
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Highlighted products for Anti-CD34 Antibody

Name
Anti-CD34 Antibody [QBEnd/10] - BSA and Azide free
Description
Mouse monoclonal [QBEnd/10] antibody to CD34.
Specificity
This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified intothree main categories, class I, class II and class III. It is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain.CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. It appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.
Applications
Flow Cytometry, IF, IHC-P
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 0.25-0.5 µg/ml
Reactivity
Human, Cynomolgus Monkey, Rhesus Monkey
Cross Reactivity
This antibody does not cross react with Rat, Sheep, Bovine, or Canine.
Immunogen
Detergent solubilized vesicular suspension prepared from human term placenta.
Host
Mouse
Clonality
Monoclonal
Clone ID
QBEnd/10
Isotype
IgG1
Light Chains
lambda
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-CD34 Antibody [QBEnd/10] (A250677).
Synonyms
CD34 antigen, CD34 molecule, CD34_HUMAN, Cluster designation 34, Hematopoietic progenitor cell antigen CD34, HPCA1, Mucosialin, OTTHUMP00000034733, OTTHUMP00000034734
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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