Anti-CD8 beta Antibody [2ST8.5H7] (A279246)

Anti-CD8 beta Antibody [2ST8.5H7]

Mouse monoclonal [2ST8.5H7] antibody to CD8 beta.

This antibody recognises the human CD8 cell surface antigen. The antibody binds to the beta chain, recognizing an epitope that is dependent upon expression of both CD8 alpha and CD8 beta.CD8 molecules are composed of dimers of either alpha/alpha or alpha/beta polypeptide combinations. Both types of dimer may co-exist at the cell surface. Clone 2ST8.5H7 is also referred to as clone T8/2T8-5H7 and binding is dependent on the expression of the alpha/beta dimer.

Flow Cytometry, WB, IP

Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Human, Cynomolgus monkey, Rhesus Monkey

Normal human T lymphocytes.

Mouse

Monoclonal

2ST8.5H7

IgG2a

Unconjugated

1 mg/ml after reconstitution.

Lyophilized

Reconstitute with 0.2 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide

Supplied in Phosphate Buffered Saline with 1% BSA.

Lyophilized: Store at 4°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Human CD8 beta antibody, clone 2ST8.5H7 recognizes the human CD8 cell surface antigen. The antibody binds to the beta chain, recognizing an epitope that is dependent upon expression of both CD8 alpha and CD8 beta.CD8 molecules are composed of dimers of either alpha/alpha or alpha/beta polypeptide combinations. Both types of dimer may co-exist at the cell surface. Clone 2ST8.5H7 is also referred to as clone T8/2T8-5H7 and binding is dependent on the expression of the alpha/beta dimer.