Anti-CD9 Antibody [Bu16] (A279883)

Anti-CD9 Antibody [Bu16]

Mouse monoclonal [Bu16] antibody to CD9.

This antibody recognises human CD9, also known as Motility-related protein-1 (MRP-1). CD9 is a 228 amino acid, including an N-terminal initiator methionine ~24-27 kDa multipass transmembrane glycoprotein and member of the tetraspanin family. It is thought that the main role of tetraspanins is to form signal transducing complexes with integrins at the cell surface, for this reason CD9 has multiple functions in cell adhesion and motility, platelet activation, gamete fusion and cell proliferation.CD9 has a functional role as a tumour metastatic suppressor and is expressed in melanomas, and colon, lung and breast carcinomas.

WB, IP, Flow Cytometry, IF

Flow Cytometry: Neat - 1:200, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

Mouse

Monoclonal

Bu16

IgG2a

Unconjugated

Protein G affinity chromatography of tissue culture supernatant.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human CD9 antibody, clone Bu16 detects human CD9, also known as Motility-related protein-1 (MRP-1). CD9 is a 228 amino acid, including an N-terminal initiator methionine ~24-27 kDa multipass transmembrane glycoprotein and member of the tetraspanin family. It is thought that the main role of tetraspanins is to form signal transducing complexes with integrins at the cell surface, for this reason CD9 has multiple functions in cell adhesion and motility, platelet activation, gamete fusion and cell proliferation.CD9 has a functional role as a tumour metastatic suppressor and is expressed in melanomas, and colon, lung and breast carcinomas.

5H9, 5H9 antigen, Antigen defined by monoclonal, BA-2/p24 antigen, BA2, BTCC 1, BTCC1, CD9 antigen, CD9 antigen p24, CD9 molecule, CD9_HUMAN, Cell growth inhibiting gene 2 protein, Cell growth-inhibiting gene 2 protein, DRAP 27, DRAP27, GIG2, Growth inhibiting gene 2 protein, Leukocyte antigen MIC3, MIC3, Motility related protein, Motility-related protein, MRP 1, MRP-1, MRP1, p24, p24 antigen, Tetraspanin 29, Tetraspanin-29, Tspan 29, Tspan-29, TSPAN29