Anti-Chromogranin A Antibody [CHGA/4219] (A277538)

Mouse monoclonal [CHGA/4219] antibody to Chromogranin A for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Chromogranin A Antibody [CHGA/4219]
Description
Mouse monoclonal [CHGA/4219] antibody to Chromogranin A.
Specificity
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 23-165, of human Chromogranin A protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
CHGA/4219
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
68-75 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Chromogranin A Antibody [CHGA/4219] - BSA and Azide free (A278126).
Synonyms
beta Granin, betagranin (N-terminal fragment of chromogranin A), catestatin, CgA, CHG A, Chga, chromofungin, Chromogranin A parathyroid secretory protein 1, Chromogranin A precursor, ChromograninA, CMGA_HUMAN, ER-37, Pancreastatin, Parastatin, Parathyroid secretory protein 1, Pituitary secretory protein I, Secretory protein I, SP I, SP-I, SP1, SPI, Vasostatin, Vasostatin I, Vasostatin II
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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