Recombinant Anti-GATA3 Antibody [GATA3/7685R] (A314991)

$765

Recombinant rabbit monoclonal [GATA3/7685R] antibody to GATA3 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-GATA3 Antibody [GATA3/7685R]
Description
Recombinant rabbit monoclonal [GATA3/7685R] antibody to GATA3.
Specificity
GATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50kDa nuclear protein regulates the development and subsequent maintenance of a variety of human tissues, including hematopoietic cells, skin, kidney, mammary gland, and the central nervous system. Among several other roles, GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67% of urothelial Carcinomas, but none of prostate or renal carcinomas.
Applications
IHC-P
Positive Control
Human breast or urothelial carcinoma tissue.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 150-250) of human GATA-3 protein. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
GATA3/7685R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
50 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
GATA 3, GATA binding factor 3, GATA binding protein 3, GATA-binding factor 3, GATA3_HUMAN, HDR, HDRS, MGC2346, MGC5199, MGC5445, Trans acting T cell specific transcription factor GATA 3, Trans-acting T-cell-specific transcription factor GATA-3
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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