Anti-GFAP Antibody [4A11] (A279334)

$355

Mouse monoclonal [4A11] antibody to GFAP for WB, IHC-P, IHC-Fr and RIA.

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4-6 Business Days
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Email
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Highlighted products for Anti-GFAP Antibody

Name
Anti-GFAP Antibody [4A11]
Description
Mouse monoclonal [4A11] antibody to GFAP.
Specificity
This antibody recognises glial fibrillary acidic protein, or GFAP, a class III intermediate filament. During development of the central nervous system, GFAP distinguishes astrocytes from other glial cells. It is involved in various cellular functions, such as cell structure and movement, cell communication and the functioning of the blood-brain barrier. It also plays a role in mitosis by adjusting the filament network present in the cell. Defects in GFAP are a cause of Alexander disease, a rare disorder of the central nervous system affecting mostly males. It is a progressive leukoencephalopathy resulting in mental and physical retardation, dementia, seizures and early death. Mouse anti Bovine GFAP antibody, clone 4A11 may be used in conjunction with Mouse anti Bovine GFAP antibody, clone 1B4 (MCA4733) and Mouse anti Bovine GFAP antibody, clone 2E1 (MCA4734) for increased sensitivity when used in immunohistology.
Applications
WB, IHC-P, IHC-Fr, RIA
Dilutions
WB: 1:500 - 1:10,000
Reactivity
Bovine, Human, Mouse, Rat, Sheep, Dog, Pig, Rabbit, Guinea Pig, Chicken
Immunogen
Bovine spinal cord homogenate.
Host
Mouse
Clonality
Monoclonal
Clone ID
4A11
Isotype
IgG2b
Conjugate

Unconjugated

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Bovine GFAP antibody, clone 4A11 recognizes glial fibrillary acidic protein, or GFAP, a class III intermediate filament. During development of the central nervous system, GFAP distinguishes astrocytes from other glial cells. It is involved in various cellular functions, such as cell structure and movement, cell communication and the functioning of the blood-brain barrier. It also plays a role in mitosis by adjusting the filament network present in the cell. Defects in GFAP are a cause of Alexander disease, a rare disorder of the central nervous system affecting mostly males. It is a progressive leukoencephalopathy resulting in mental and physical retardation, dementia, seizures and early death. Mouse anti Bovine GFAP antibody, clone 4A11 may be used in conjunction with Mouse anti Bovine GFAP antibody, clone 1B4 (MCA4733) and Mouse anti Bovine GFAP antibody, clone 2E1 (MCA4734) for increased sensitivity when used in immunohistology.
Synonyms
ALXDRD, cb345, etID36982.3, FLJ42474, FLJ45472, gfapl, GFAP_HUMAN, Glial fibrillary acidic protein, Intermediate filament protein, wu:fb34h11, wu:fk42c12, xx:af506734, zgc:110485
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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