Anti-hnRNP K Antibody [F45 P9 C7] (A280432)

Anti-hnRNP K Antibody [F45 P9 C7]

Mouse monoclonal [F45 P9 C7] antibody to hnRNP K.

This antibody recognises hnRNP K (heterogeneous ribonucleotide protein K), a 464 amino acid acidic protein found in the nucleus, cytoplasm and mitochondria, involved in transcription, mRNA shuttling and the translation and editing of RNA.Over-expression of hnRNP K has been demonstrated in cancerous tissue including that of the colon, breast, liver and lungs, and its involvement in cell migration has been implicated in tumour metastasis. hnRNP K increases the transcriptional activity of the c-myc and c-src oncogenes.

WB, IHC-P

IHC-P 1: 1:200 - 1:500

Species Independent, Rat, Rabbit, Mouse, Chicken, Human

Ovalbumin-conjugated synthetic peptide SVKQYSGKFF.

SVKQYSGKFF

Mouse

Monoclonal

F45 P9 C7

IgG1

1 mg/ml

Approximately 51 kDa in Calu6 and HT29 cell lysates.

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti hnRNP K antibody, clone F45 P9 C7 recognizes hnRNP K (heterogeneous ribonucleotide protein K), a 464 amino acid acidic protein found in the nucleus, cytoplasm and mitochondria, involved in transcription, mRNA shuttling and the translation and editing of RNA.Over-expression of hnRNP K has been demonstrated in cancerous tissue including that of the colon, breast, liver and lungs, and its involvement in cell migration has been implicated in tumour metastasis. hnRNP K increases the transcriptional activity of the c-myc and c-src oncogenes (Wang et al. 2020).

Heterogeneous nuclear ribonucleoprotein K, HNRNPK, HNRPK, Transformation up-regulated nuclear protein, TUNP