Anti-IL-6 Antibody - BSA and Azide free (A283015)

Anti-IL-6 Antibody - BSA and Azide free

Rabbit polyclonal antibody to IL-6.

This antibody recognises human IL-6 (Interleukin-6), a 184 amino acid multifunctional pro-inflammatory cytokine, secreted by activated T cells, macrophages, endothelial cells, fibroblasts and osteoblasts.The diverse biological properties of IL-6 include the principle inducer of the acute phase response in the liver, stimulation of B cell differentiation and subsequent immunoglobulin production, promotion of hybridoma growth, regulation of bone metabolism and stimulation of energy mobilization in muscle and fatty tissue. IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6Ra chain (CD126) and the signal-transducing component gp130 (CD130), but can also stimulate cells expressing gp130 through a soluble IL-6R. Rabbit anti Human Interleukin-6 antibody has been shown to inhibit the biological activity of Human IL-6.

IF, WB, ELISA, IHC-P, Functional Assays

ELISA: 0.5 µg/ml, Functional Assays 1: 0.20 - 0.40 µg/ml, IHC-P 2: 0.25 - 0.5 µg/ml, WB: 0.1 - 0.2 µg/ml

Human

Recombinant human IL-6.

Rabbit

Polyclonal

IgG

Unconjugated

1 mg/ml after reconstitution.

Reconstitute with 0.1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human Interleukin-6 antibody is specific for human IL-6 (Interleukin-6), a 184 amino acid multifunctional pro-inflammatory cytokine, secreted by activated T cells, macrophages, endothelial cells, fibroblasts and osteoblasts.The diverse biological properties of IL-6 include the principle inducer of the acute phase response in the liver, stimulation of B cell differentiation and subsequent immunoglobulin production, promotion of hybridoma growth, regulation of bone metabolism and stimulation of energy mobilization in muscle and fatty tissue. IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6Ra chain (CD126) and the signal-transducing component gp130 (CD130), but can also stimulate cells expressing gp130 through a soluble IL-6R. Rabbit anti Human Interleukin-6 antibody has been shown to inhibit the biological activity of Human IL-6.

B cell differentiation factor , B cell stimulatory factor 2, B-cell stimulatory factor 2, BSF 2, BSF-2, BSF2, CDF, CTL differentiation factor, Cytotoxic T cell differentiation factor , Hepatocyte stimulating fact, Hepatocyte stimulating factor, Hepatocyte stimulatory factor, HGF, HPGF, HSF , Hybridoma growth factor, Hybridoma growth factor Interferon beta-2, Hybridoma plasmacytoma growth factor , IFN-beta-2, IFNB2 , IL 6, IL6, IL6 protein , IL6_HUMAN, Interferon beta 2, Interferon beta-2, Interleukin 6, Interleukin 6 (interferon beta 2) , Interleukin BSF 2, Interleukin BSF2, Interleukin-6, Interleukin6