Endothelial cells play many critical roles in the cardiovascular system by lining blood vessels and participating in various physiological processes, including vasodilation, coagulation, inflammation, and angiogenesis. To study these cells, researchers utilize a range of specific markers that help identify and characterize endothelial cell populations. These markers aid in understanding the heterogeneity of endothelial cells, their functional roles, and identifying potential therapeutic targets. Cluster of Differentiation 31, also known as Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1), for example, is one of the most widely used endothelial cell markers. CD31 is a transmembrane glycoprotein expressed at endothelial cell junctions, and plays a key role in cell adhesion, leukocyte migration, and platelet aggregation. It is highly specific to endothelial cells and is used for their identification in histological sections and flow cytometry. Von Willebrand Factor is a large glycoprotein synthesized and stored in endothelial cells. It plays a critical role in initiating blood clotting by mediating platelet adhesion and binding to collagen at sites of vascular injury. VWF is released upon endothelial activation and injury, making it a valuable marker for both quiescent and activated endothelial cells. Endoglin (CD105) is a co-receptor for transforming growth factor-beta (TGF-β) and is predominantly expressed on activated endothelial cells, being involved in angiogenesis and vascular remodelling. CD105 is commonly used in studies of endothelial cell activation and angiogenic processes. Tie-2 (TEK) is a receptor tyrosine kinase primarily expressed by endothelial cells in blood vessels. It interacts with the angiopoietin ligands and is essential for vascular stability and angiogenesis. The expression of Tie-2 is associated with the endothelial cell lineage and is utilized to identify and study endothelial cells during development and disease. Vascular Endothelial (VE)-Cadherin (CD144) is a transmembrane adhesion molecule that plays a crucial role in maintaining endothelial cell junctions and barrier integrity. It is specifically expressed by endothelial cells and is important for mediating cell-cell adhesion within the vascular endothelium. Intercellular Adhesion Molecule-1 (ICAM-1) and Vascular Cell Adhesion Molecule-1 (VCAM-1) are cell adhesion molecules expressed on activated endothelial cells. They facilitate monocyte adhesion and migration during inflammation. These markers are often used to study the interactions between endothelial cells and immune cells in various cardiovascular diseases. CD146, also known as Melanoma Cell Adhesion Molecule (MCAM), is expressed on both endothelial cells and pericytes. It is involved in cell adhesion, angiogenesis, and vascular stability. CD146 is useful in characterizing endothelial cells in various physiological and pathological conditions. Another CD marker, CD34, is a cell surface glycoprotein expressed by hematopoietic stem cells and endothelial progenitor cells. While it is not exclusively endothelial-specific, CD34 is commonly used in studies involving angiogenesis and endothelial cell differentiation. Finally, CD133 (also known as Prominin-1) is expressed by endothelial progenitor cells and has been linked to angiogenesis and vasculogenesis. CD133 expression helps identify immature endothelial cells during vascular development. We offer a large product range of research tools for investigating endothelial cell markers, including CD31 antibodies, CD105 antibodies, VEGF Receptor 2 antibodies, CD105 ELISA Kits, and Thrombomodulin ELISA Kits. Explore our full endothelial cell markers product range below and discover more, for less.