Anti-SIRT3 Antibody [PCRP-SIRT3-1C10] - BSA and Azide free (A278203)

Mouse monoclonal [PCRP-SIRT3-1C10] antibody to SIRT3 for ELISA, IP, Flow Cytometry, IF and WB.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-SIRT3 Antibody [PCRP-SIRT3-1C10] - BSA and Azide free
Description
Mouse monoclonal [PCRP-SIRT3-1C10] antibody to SIRT3.
Specificity
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
Applications
ELISA, IP, Flow Cytometry, IF, WB
Dilutions
IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human SIRT3 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-SIRT3-1C10
Isotype
IgG2a
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
43.57 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-SIRT3 Antibody [PCRP-SIRT3-1C10] (A277615).
Synonyms
hSIRT 3, hSIRT3, Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase, NAD dependent deacetylase sirtuin 3 mitochondrial, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, Regulatory protein SIR2 homolog 3, Silent mating type information regulation 2 S.cerevisiae homolog 3, Sir 2 like 3, SIR 2 like protein 3, SIR 3, SIR2 L3, Sir2 like 3, SIR2 like protein 3, SIR2-like protein 3, SIR2L3, SIR3_HUMAN, SIRT 3, Sirtuin 3, Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae), Sirtuin type 3, Sirtuin3
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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