Anti-TNF alpha Antibody [B-C7] (A279798)

Anti-TNF alpha Antibody [B-C7]

Mouse monoclonal [B-C7] antibody to TNF alpha.

This antibody recognises human tumor necrosis factor, also known as Cachectin or Tumor necrosis factor ligand superfamily member 2. TNFa exists as a 233 amino acid membrane bound form, a single pass type II transmembrane protein which can be cleaved between residues 76 and 77 by ADAM17, also known as CD156b to yield the 157 amino acid soluble form of TNFa (UniProt: P01375).recognises both natural and bacterially producted recombinant human TNF-alpha and has an affinity of Kd = 0.5nM. Mouse anti Human TNF alpha antibody, clone B-C7 demonstrates neutralising activity against human TNF-alpha. Removal of sodium azide is recommended prior to functional assays.

Human

This antibody does not cross react with Mouse

Recombinant human TNF-alpha.

Mouse

Monoclonal

B-C7

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human TNF alpha antibody, clone B-C7 recognizes human tumor necrosis factor, also known as Cachectin or Tumor necrosis factor ligand superfamily member 2. TNFa exists as a 233 amino acid membrane bound form, a single pass type II transmembrane protein which can be cleaved between residues 76 and 77 by ADAM17, also known as CD156b to yield the 157 amino acid soluble form of TNFa (UniProt: P01375).Mouse anti Human TNF alpha antibody, clone B-C7 recognizes both natural and bacterially producted recombinant human TNF-alpha and has an affinity of Kd = 0.5nM. Mouse anti Human TNF alpha antibody, clone B-C7 demonstrates neutralising activity against human TNF-alpha. Removal of sodium azide is recommended prior to functional assays.

Cachectin, TNF, TNF-a, TNF-alpha, TNFA, TNFSF2, Tumor necrosis factor, Tumor necrosis factor ligand superfamily member 2