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Anti-TNF alpha Antibody

Mouse monoclonal (CH8810) antibody to Tumor Necrosis Factor alpha from Anogen (MO-C40003A).
Name: Anti-TNF alpha Antibody
Description: Mouse monoclonal (CH8810) antibody to Tumor Necrosis Factor alpha.
Specificity: This antibody recognises both recombinant and native human TNF-α.
Applications: ELISA, IHC
Reactivity: Human
Immunogen: Purified recombinant human TNF-α.
Host: Mouse
Clonality: Monoclonal
Clone: CH8810
Myeloma: Sp2/0-Ag14
Isotype: IgG1
Conjugate: Unconjugated
Concentration: Reconstitution dependent.
Purity: Protein G affinity chromatagraphy.
Product Form: Lyophilised
Reconstitution: Reconstitute with double distilled water.
Formulation: Lyophilised from a solution of 0.01M Phosphate Buffered Saline, pH 7.0.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Introduction: Tumor Necrosis Factor-alpha (TNF-α) is a multifunctional pro-inflammatory cytokine, mainly secreted by activated macrophages. TNF-α was named for its remarkable ability to cause hemorrhagic necrosis to tumors in mice. It is implicated with a variety of biological procedures including systemic inflammation, cell proliferation, apoptosis, lipid metabolism, and coagulation. The pleiotropic attribute of TNF-α regulation is associated with its ability to trigger multiple signalling pathways simultaneously. It is well documented that TNF-α functions through its receptors, TNFR1 (p55) and TNFR2 (p75). TNF-α not only contributes to the immune response to bacterial, fungal, viral and parasitic invasions, but also functions in tissue remodeling, autoimmune-diseases and the necrosis of specific tumors. TNF-α hyper-expression in response to some bacterial components such as LPS can cause life threatening septic shock. Recombinant TNF-α, in combination with chemotherapy, has been applied for treatment of soft sarcomas, melanomas and other irresectable tumors. Anti-TNF-α therapy has been used for treatment of rheumatoid arthritis.
Synonyms: APC1 Antibody
APC1 protein Antibody
Cachectin Antibody
DIF Antibody
Differentiation inducing factor Antibody
Macrophage cytotoxic factor Antibody
Tnf Antibody
TNF superfamily, member 2 Antibody
TNF, macrophage derived Antibody
TNF, monocyte derived Antibody
TNF-a Antibody
TNF-alpha Antibody
TNFA Antibody
TNFA_HUMAN Antibody
TNFSF2 Antibody
Tumor necrosis factor Antibody
Tumor necrosis factor alpha Antibody
Tumor necrosis factor ligand superfamily member 2 Antibody
Tumor Necrosis Factor, Membrane Form Antibody
Tumor necrosis factor, soluble form Antibody
Description: Rabbit polyclonal antibody to TNF.
Application: WB, IHC
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

£148 – £372

Description: Rabbit polyclonal antibody to APC1 (E684)
Application: IHC, IF
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 650-698 of Human APC1.

£165 – £283

Description: Rabbit polyclonal antibody to APC1
Application: E, WB, IHC
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: Raised against a 17 amino acid peptide near the carboxy terminus of human APC1.

£301

Description: Rabbit polyclonal antibody to TNF
Application: IHC
Host: Rabbit
Reactivity: Human
Immunogen: Fusion protein corresponding to a region derived from internal residues of human tumor necrosis factor

£234

Please Note: Anti-TNF alpha Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | MO-C40003A
Size Price Quantity
100µg £239
500µl £342

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Lead Time: Currently 4-6 Days
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe