Recombinant Anti-TNF alpha Antibody [TNF/1500R] - BSA and Azide free (A253336)

Recombinant rabbit monoclonal [TNF/1500R] antibody to TNF alpha for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com

Highlighted products for Anti-TNF alpha Antibody

Name
Anti-TNF alpha Antibody [TNF/1500R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [TNF/1500R] antibody to TNF alpha.
Specificity
This antibody recognizes human 17-26kDa protein, which is identified as cytokine TNF-alpha (Tumor Necrosis Factor-alpha). TNF-alpha can be expressed as a 17kDa free molecule, or as a 26kDa membrane protein. TNF-alpha is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
Applications
IHC-P
Dilutions
IHC-P: 4-8 µg/ml
Reactivity
Human, Rat
Immunogen
Recombinant full-length human TNF alpha protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
TNF/1500R
Isotype
IgG
Conjugate

Unconjugated

Concentration
1 mg/ml
Molecular Weight
17 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-TNF alpha Antibody [TNF/1500R] (A250156).
Synonyms
APC1, APC1 protein, Cachectin, DIF, Differentiation inducing factor, Macrophage cytotoxic factor, soluble form, Tnf, TNF a, TNF macrophage derived, TNF monocyte derived, TNF superfamily member 2 , TNF superfamily, member 2, TNF, macrophage derived, TNF, monocyte derived, TNF-a, TNF-alpha, TNFA, TNFA_HUMAN, TNFSF2, Tumor necrosis factor, Tumor necrosis factor (TNF superfamily member 2) , Tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, Tumor Necrosis Factor, Membrane Form, Tumor necrosis factor, soluble form
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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