Anti-Tyrosine Hydroxylase Antibody (A283964)

$645

Rabbit polyclonal antibody to Tyrosine Hydroxylase for WB, IHC-P, IHC-Fr and IF.

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Tyrosine Hydroxylase Antibody
Description
Rabbit polyclonal antibody to Tyrosine Hydroxylase.
Specificity
This antibody recognises tyrosine hydroxylase (TH). Tyrosine hydroxylase catalyses the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain.Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.
Applications
WB, IHC-P, IHC-Fr, IF
Dilutions
IF: 1:1,000, IHC-Fr: 1:1,000, WB: 1:1,000
Reactivity
Rat, Mammals, Grasshopper (Gastrimargus musicus), Rat, Mouse
Immunogen
Tyrosine hydroxylase purified from pheochromocytoma.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
Lot Specific
Molecular Weight
Approximately 60 kDa in rat caudate cell lysates.
Product Form
Liquid
Formulation
Supplied in 10mM HEPES, pH 7.5, with 0.01% BSA, 50% Glycerol, and 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Rat tyrosine hydroxylase antibody recognizes tyrosine hydroxylase (TH). Tyrosine hydroxylase catalyses the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease (Haavik et al. 1998).
Synonyms
Dystonia 14, DYT14, DYT5b, EC 1.14.16.2, OTTHUMP00000011225, OTTHUMP00000011226, ple, Protein Pale, TH, The, TY3H_HUMAN, TYH, Tyrosine 3 hydroxylase, Tyrosine 3 monooxygenase, Tyrosine 3-hydroxylase, Tyrosine 3-monooxygenase
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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