Anti-eIF4EBP1 (phospho Ser65) Antibody (A283544)

Anti-eIF4EBP1 (phospho Ser65) Antibody

Rabbit polyclonal antibody to eIF4EBP1 (phospho Ser65).

WB: 1:500 - 1:2,000

Human, Mouse, Rat

Phospho-specific peptide corresponding to residues surrounding Ser65 of human 4EBP1.

Rabbit

Polyclonal

IgG

Lot Specific

Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) is also known as phosphorylated heat-and acid-stable protein regulated by insulin 1 (PHAS-I), when phosphorylated at serine 65. 4EBP1 belongs to the eIF4E-binding protein family. 4EBP1, when bound to eIF4E, inhibits cap-dependent translation. Phosphorylation at serine 65 inhibits binding of 4EBP1 to eIF4F allowing cap-dependent translation.

4E-BP1, eIF4E-binding protein 1, Eukaryotic translation initiation factor 4E-binding protein 1, PHAS-I, Phosphorylated heat- and acid-stable protein regulated by insulin 1