Anti-SSTR3 Antibody (A334545)

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This product is discontinued

Anti-SSTR3 Antibody (A334545) has been discontinued and is no longer available.

View all SSTR3 Antibodies.

Specifications

Name

Anti-SSTR3 Antibody

Description

Rabbit polyclonal antibody to SSTR3.

Specificity

This antibody binds specifically to the C-terminal region of human SST3, detecting the non-phosphorylated form. It is optimized for Western blot analysis, facilitates immunoprecipitation from tissue lysates, and supports immunohistochemistry in cultured cells and tissue sections.

Applications

WB, ICC, IHC

Dilutions

WB: 1,000, IHC: 1:100, ICC: 1:200

Reactivity

Human

Immunogen

Synthetic peptide corresponding to human SST3 (amino acids. 398-418). Immunogen range is 22-22 amino acids.

Sequence

QLLPQEASTGEKSSTMRISYL

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugate

Unconjugated

Purification

Antigen affinity purification.

Concentration

Lot Specific

Product Form

Liquid

Formulation

Supplied in Dulbecco's PBS, pH 7.4, with 150 mM NaCl and 0.005% Sodium Azide.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze/thaw cycles.

Synonyms

Somatostatin receptor type 3, SS-3-R, SS3-R, SS3R, SSR-28, SST3

Isotype Controls

Suitable Secondaries

See all Anti-Rabbit IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation DataValidation Data (3)

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Anti-SSTR3 Antibody (A334545)

Western blot validation of Somatostatin Receptor 3 (SST3) in transfected HEK293 cells. Lysates from native HEK293 cells (MOCK) or cells stably expressing SST3 were probed with phosphorylation-independent anti-SST3 antibody (A334545) at 1:1000.

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Immunohistochemistry - Anti-SSTR3 Antibody (A334545)

Immunocytochemical detection of Somatostatin Receptor 3 (SST3) in HEK293 cells. HEK293 cells stably expressing SST3 were untreated or treated with 1 µM SRIF for 30 min and stained with anti-SST3 antibody (A334545) at 1:200. SST3 receptors were confined to the plasma membrane in untreated cells (0 min) and observed in perinuclear vesicular clusters after 30 min of SRIF exposure.

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Immunohistochemistry - Anti-SSTR3 Antibody (A334545)

Immunohistochemical localization of Somatostatin Receptor 3 (SST3) in human growth-hormone-producing pituitary adenoma. Tumor sections were dewaxed, microwaved in citric acid, and stained with anti-SST3 antibody (A334545) at 1:100, followed by biotinylated anti-rabbit IgG and avidin-biotin solution. Color was developed with 3-amino-9-ethylcarbazole (AEC), and sections were counterstained with hematoxylin. SST3 receptors were uniformly detected at the plasma membrane of nearly all tumor cells.