Anti-STAT3 Antibody (A320057)

Anti-STAT3 Antibody

Goat polyclonal antibody to STAT3.

This antibody recognises an epitope within the C-terminal (CT) region of signal transducer and activator of transcription 3 (STAT3), an 80-85 kDa member of the STAT protein family, which plays an important role in cell growth, survival differentiation and transformation, transducing signals from cytokine receptors to the nucleus. STAT3 is phosphorylated in response to cytokines and growth factors including interleukin-5, interleukin-6, epidermal growth factor and leukaemia inhibitory factor. It is expressed in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

WB, IHC-P, ELISA, IHC-Fr

ELISA: 1:32,000, IHC-Fr 1: 10 µg/ml, WB: 0.5 - 5 µg/ml. A minimum incubation time of 1 hour is recommended with this antibody.

Human, Mouse, Rat

A peptide sequence of DMELTSECARSPM corresponding to the C-terminus of STAT3 (NP_003141.2; NP_644805.1).

DMELTSECARSPM

Goat

Polyclonal

IgG

Approximately 80-85 kDa in A431 cell lysates. A minimum incubation time of 1 hour is recommended with this antibody.

Liquid

Supplied in TRIS Buffered Saline, 0.5% BSA and 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Goat anti Mouse STAT3 antibody recognizes an epitope within the C-terminal (CT) region of signal transducer and activator of transcription 3 (STAT3), an 80-85 kDa member of the STAT protein family, which plays an important role in cell growth, survival differentiation and transformation, transducing signals from cytokine receptors to the nucleus. STAT3 is phosphorylated in response to cytokines and growth factors including interleukin-5, interleukin-6, epidermal growth factor and leukaemia inhibitory factor. It is expressed in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Acute-phase response factor, APRF, Signal transducer and activator of transcription 3