Anti-CD34 Antibody [QBEnd/10 + HPCA1/763] (A250680)

Mouse monoclonal [QBEnd/10 + HPCA1/763] antibody to CD34 for Flow Cytometry, IF and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com

Highlighted products for Anti-CD34 Antibody

Name
Anti-CD34 Antibody [QBEnd/10 + HPCA1/763]
Description
Mouse monoclonal [QBEnd/10 + HPCA1/763] antibody to CD34.
Specificity
This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.
Applications
Flow Cytometry, IF, IHC-P
Dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 0.25-0.5 µg/ml
Reactivity
Human
Immunogen
Clone QBEnd/10: Detergent solubilized vesicular suspension prepared from human term placenta. Clone HPCA1/763: Recombinant full-length human HPCA1 protein.
Host
Mouse
Clonality
Oligoclonal
Clone ID
QBEnd/10 + HPCA1/763
Isotype
IgG1, lambda + IgG1, lambda
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
90-110 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes

Please note, this product is an oligoclonal antibody; it is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies not only have the specificity and batch-to-batch consistency of a monoclonal antibody, but they also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen.

This oligoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CD34 Antibody [QBEnd/10 + HPCA1/763] - BSA and Azide free (A253860).

Synonyms
CD34 antigen, CD34 molecule, CD34_HUMAN, Cluster designation 34, Hematopoietic progenitor cell antigen CD34, HPCA1, Mucosialin, OTTHUMP00000034733, OTTHUMP00000034734
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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