Anti-AHSG Antikörper [AHSG/3748] (A277583)

Name: Anti-AHSG Antibody [AHSG/3748]
Brand: Antibodies.com
SKU: A277583
Price: 525.0 USD
Availability: InStock

Bild Vergrößern

$525

Monoklonal [AHSG/3748] Maus Antikörper gegen AHSG für IHC-P.

100% Qualitätsgarantie

Preis-Match-Garantie

Alternative Formats and ConjugatesAlternative Formats

Carrier Free and Preservative Free

Versand

Versandkosten

$40

Vorlaufzeit

Lieferung in 4-6 Werktagen

Kontakt

Telefon

+1 (314) 370-6046

orders@antibodies.com

Garantien

100% Qualitätsgarantie

Preis-Match-Garantie

Stichworte:

Monospezifischer Antikörper

Produktdetails

Produktname

Anti-AHSG Antibody [AHSG/3748]

Beschreibung

Mouse monoclonal [AHSG/3748] antibody to AHSG.

Spezifität

Fetuin (also designated Î±2-z-globulin or Î±2-HS-glycoprotein) is a secreted plasma protein that is expressed in hepatocytes, monocyte/macrophages and in bone and is downregulated during injury and inflammation. Fetuin preferentially binds to and carries calcium and barium ions in the blood, where it is thought to mediate serum calcium homeostasis and mineralization, and to potentially participate in the transport of bioactive molecules. Additionally, fetuin has been shown to function as an acute phase anti-inflammatory mediator that is critical to regulating the innate immune response following tissue injury. During inflammation, circulating fetuin levels substantially decrease as fetuin becomes associated with the membranes of macrophages. This membrane associated form of fetuin acts as an opsonic participant by potentiating the entry of cationic small molecules into the activated macro-phage, which in turn facilitates macrophage-deactivating mechanisms. Biologically active fetuin is derived from a precursor protein that is cleaved at the aminoterminus to generate two chains held together by a single disulfide bond.

Anwendungen

IHC-P

Verdünnungen

IHC-P: 1-2 µg/ml

Reaktivität

Human

Immunogen

Recombinant fragment corresponding to human AHSG protein. The exact sequence is proprietary.

Wirt

Mouse

Klonalität

Monoclonal

Klon

AHSG/3748

Isotyp

IgG1

Leichte Ketten

kappa

Konjugat

Unconjugated

Reinigung

Protein A/G chromatography.

Konzentration

200 µg/ml

Molekulargewicht

59 kDa

Produktform

Liquid

Formulierung

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Lagerung

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Allgemeine Hinweise

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-AHSG Antibody [AHSG/3748] - BSA and Azide free (A278171).

Synonyme

59 kDa bone sialic acid-containing protein, A2HS, Aa2-066, AHS, Ahsg alpha-2-HS-glycoprotein, Alpha 2 HS Glycoprotein, Alpha 2 Z globulin, Alpha-2-HS-glycoprotein, Alpha-2-HS-glycoprotein chain B, Alpha-2-Z-globulin, Asialofetuin, Ba alpha 2 glycoprotein, Ba-alpha-2-glycoprotein, BSP, Countertrypin, Fetua, FETUA_HUMAN, Fetuin , mouse, homolog of, Fetuin A, Fetuin-A, Glycoprotein PP63, HSGA, pp63

Isotyp-Kontrollantikörper

Kompatible Sekundärantikörper

Haftungsausschluss

Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Produktbilder (3)

Bild Vergrößern

Figure 1: Immunohistochemistry - Anti-AHSG Antibody [AHSG/3748] (A277583)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human placenta tissue using Anti-AHSG Antibody [AHSG/3748] at 2µg/ml. Inset: PBS instead of the primary antibody. Secondary antibody negative control.

Bild Vergrößern

Figure 2: SDS-PAGE - Anti-AHSG Antibody [AHSG/3748] (A277583)

SDS-PAGE analysis of Anti-AHSG Antibody [AHSG/3748] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

Bild Vergrößern

Figure 3: Anti-AHSG Antibody [AHSG/3748] (A277583)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-AHSG Antibody [AHSG/3748]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.