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Anti-alpha 1 Antichymotrypsin Antikörper [AACT/1451 + AACT/1452] (A277554)

Oligoclonal [AACT/1451 + AACT/1452] Maus Antikörper gegen alpha 1 Antichymotrypsin für IHC-P.

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Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
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Email
orders@antibodies.com
Produktname
Anti-alpha 1 Antichymotrypsin Antibody [AACT/1451 + AACT/1452]
Beschreibung
Mouse monoclonal [AACT/1451 + AACT/1452] antibody to alpha 1 Antichymotrypsin.
Spezifität
It recognizes a protein of 65-76kDa, which is identified antichymotrypsin (AACT). AACT is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human, the normal serum level of AACT is about one-tenth that of α 1-antitrypsin (AAT), with which it shares nucleic acid and protein sequence homology. Both are major acute phase reactants; their concentrations in plasma increase in response to trauma, surgery and infection. Elevated levels of AACT are widely, but not universally, reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the diagnosis of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACTantibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity.
Anwendungen
IHC-P
Verdünnungen
IHC-P: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant fragment, around amino acids 49-187, of human alpha 1 Antichymotrypsin. The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Oligoclonal
Klon
AACT/1451 + AACT/1452
Isotyp
IgG1 + IgG1
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
65-76 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise

Please note, this product is an oligoclonal antibody; it is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies not only have the specificity and batch-to-batch consistency of a monoclonal antibody, but they also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen.

This oligoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-alpha 1 Antichymotrypsin Antibody [AACT/1451 + AACT/1452] - BSA and Azide free (A278142).

Synonyme
AACT, AACT_HUMAN, ACT, Alpha-1-antichymotrypsin His-Pro-less, Antichymotrypsin, Cell growth inhibiting gene 24/25 protein, Cell growth-inhibiting gene 24/25 protein, GIG24, GIG25, Growth inhibiting protein 24, Growth inhibiting protein 25, MGC88254, Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase, antitrypsin) member 3, Serine (or cysteine) proteinase inhibitor clade A member 3, Serine proteinase inhibitor clade A member 3, Serpin A3, Serpin family A member 3, Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3, SERPINA3
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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