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Anti-BCL11A Antikörper [PCRP-BCL11A-1G10] (A277750)

Monoklonal [PCRP-BCL11A-1G10] Maus Antikörper gegen BCL11A für ELISA, WB, IP, Flow Cytometry und IF.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
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Email
orders@antibodies.com
Produktname
Anti-BCL11A Antibody [PCRP-BCL11A-1G10]
Beschreibung
Mouse monoclonal [PCRP-BCL11A-1G10] antibody to BCL11A.
Spezifität
Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.
Anwendungen
ELISA, WB, IP, Flow Cytometry, IF
Verdünnungen
WB: 1-2 µg/ml, IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reaktivität
Human
Kreuzreaktivität
This antibody is predicted to cross react with Mouse and Rat.
Immunogen
Recombinant full-length human BCLL1A protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
PCRP-BCL11A-1G10
Isotyp
IgG2a
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Molekulargewicht
91.2 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-BCL11A Antibody [PCRP-BCL11A-1G10] - BSA and Azide free (A278338).
Synonyme
2810047E18Rik, B cell CLL/lymphoma 11A (zinc finger protein), B cell CLL/lymphoma 11A (zinc finger protein) isoform 2, B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BC11A_HUMAN, BCL-11A, BCL11A B cell CLL/lymphoma 11A (zinc finger protein) isoform 1, BCL11A L, BCL11A S, BCL11A XL, BCL11a-M, BCL11AL, BCL11AS, BCL11AXL, C2H2 type zinc finger protein, COUP TF interacting protein 1, COUP-TF-interacting protein 1, Ctip1, CTIP1, mouse, homolog of, D930021L15Rik, Ecotropic viral integration site 9, Ecotropic viral integration site 9 homolog, Ecotropic viral integration site 9 protein, Ecotropic viral integration site 9 protein homolog, EVI-9, Evi9, Evi9, mouse, homolog of, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, mKIAA1809, OTTHUMP00000159788, OTTHUMP00000159789, OTTHUMP00000201250, OTTHUMP00000202084, Zinc finger protein 856, ZNF856
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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