Rekombinant Anti-Calbindin Antikörper [rCALB1/8499] (A314535)

Anti-Calbindin Antibody [rCALB1/8499]

Recombinant mouse monoclonal [rCALB1/8499] antibody to Calbindin.

The family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.

IHC-P

293T or HepG2 cells. Human prostate, lung, pancreas, kidney or liver.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 7-96) of human CALB1 protein. The exact sequence is proprietary.

Mouse

Monoclonal

rCALB1/8499

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

52 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

avian-type, CAB27, CALB, CALB 1, CALB1, CALB1_HUMAN, Calbindin 1 28kDa, Calbindin D28, D 28K, D-28K, D28K, OTTHUMP00000166027, OTTHUMP00000225441, RTVL H protein, Vitamin D dependent calcium binding protein, Vitamin D dependent calcium binding protein avian type, Vitamin D-dependent calcium-binding protein