Anti-Carcinoembryonic Antigen Antikörper [C66/195] (A248128)

Anti-Carcinoembryonic Antigen Antibody [C66/195]

Mouse monoclonal [C66/195] antibody to Carcinoembryonic Antigen.

This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb reacts with nonspecific cross-reacting antigen (NCA) and shows a cross-reaction with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Flow Cytometry, IF, IHC-P

Flow Cytometry: 0.5-1 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human, Monkey

Purified human CEA protein.

Mouse

Monoclonal

C66/195

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

80-200 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Carcinoembryonic Antigen Antibody [C66/195] - BSA and Azide free (A251311).

Carcinoembryonic antigen related cell adhesion molecule 5, Carcinoembryonic antigen-related cell adhesion molecule 5, CD66e, CD66e antigen, CEA, CEACAM5, CEAM5_HUMAN, Meconium antigen 100