+1 (314) 370-6046 oderKontakt

Anti-CD163 Antikörper [EDHu-1] (PE) (A280343)

$515

Monoklonal [EDHu-1] Maus Antikörper gegen CD163 (PE) für Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-CD163 Antibody [EDHu-1] (PE)
Beschreibung
Mouse monoclonal [EDHu-1] antibody to CD163 (PE).
Spezifität
This antibody recognises the human CD163 cell surface antigen, a 130-140 kDa glycoprotein expressed by tissue macrophages. CD163 expression may be induced on monocytes by culture in dexamethasone.Clone EDHu-1 is reported to inhibit the binding of haptoglobin/hemoglobin to CD163. Truncation mutation analysis demonstrates binding of EDHu-1 occurs via the N-terminal region of CD163 containing the first three scavenger receptor, Cysteine-rich, SRCR domains the third domain being critical as, cleavage of this domain at the major cleavage site ASP-265 abrogates binding to the N-terminal fragment.
Anwendungen
Flow Cytometry
Verdünnungen
Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 106 cells in 100µl
Reaktivität
Human, Rhesus Monkey, Sheep, Pig, Guinea Pig, Bovine, Cynomolgus monkey
Immunogen
Leucocytes harvested from the pleural cavity of patients with idiopathic spontaneous pneumothorax.
Wirt
Mouse
Klonalität
Monoclonal
Klon
EDHu-1
Isotyp
IgG1
Konjugat

PE

Excitation: 565nm, Emission: 578nm

Reinigung
Protein A affinity chromatography of tissue culture supernatant.
Konzentration
Reconstitution dependent.
Produktform
Lyophilized
Rekonstitution
Reconstitute with 1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution.
Formulierung
Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.
Lagerung
Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light.
Allgemeine Hinweise
Mouse anti Human CD163 antibody, clone EDHu-1 recognizes the human CD163 cell surface antigen, a 130-140 kDa glycoprotein expressed by tissue macrophages. CD163 expression may be induced on monocytes by culture in dexamethasone.Clone EDHu-1 is reported to inhibit the binding of haptoglobin/hemoglobin to CD163 (Madsen et al. 2004).Truncation mutation analysis demonstrates binding of EDHu-1 occurs via the N-terminal region of CD163 containing the first three scavenger receptor, Cysteine-rich, SRCR domains the third domain being critical as, cleavage of this domain at the major cleavage site ASP-265 abrogates binding to the N-terminal fragment.
Synonyme
C163A_HUMAN, CD 163, CD163 antigen, CD163 molecule, Hemoglobin scavenger receptor, M130, M130 antigen precursor, Macrophage associated antigen, MM130, OTTHUMP00000238617, OTTHUMP00000238618, OTTHUMP00000238619, OTTHUMP00000238620, SCARI1, Scavenger receptor cysteine rich type 1 protein M130, sCD163, Soluble CD163
Isotyp-Kontrollantikörper
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

Alternative Produkte zum Anti-CD163 Antikörper [EDHu-1] (PE) (A280343)

Oben