Anti-Collagen VII Antikörper [LH7.2] (A248248)

Anti-Collagen VII Antibody [LH7.2]

Mouse monoclonal [LH7.2] antibody to Collagen VII.

This antibody recognizes an epitope located on collagenase digested Type VII collagen (150kDa), i.e. the non-helical carboxyl terminal region of the dimer. Binding is localized at the inferior border of the lamina densa as demonstrated by immunoelectron microscopy. Type VII is also found in the retina, where its function is unknown. It interacts with Laminin 5 and Fibronectin. Collagen VII is a stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.

ELISA, WB, IF, IHC-P

WB: 1-2 µg/ml, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Human, Sheep, Goat, Horse, Guinea Pig, Bovine

Recombinant full-length human Collagen VII protein.

Mouse

Monoclonal

LH7.2

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

290 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Collagen VII Antibody [LH7.2] - BSA and Azide free (A251430).

Alpha 1 type VII collagen, CO7A1_HUMAN, Col7a1, Collagen alpha 1(VII) chain, Collagen alpha-1(VII) chain, Collagen type VII alpha 1, Collagen VII alpha 1 polypeptide, CollagenVII, EBD 1, EBD1, EBDCT, EBR 1, EBR1, LC collagen, Long chain collagen, Long-chain collagen