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Anti-Decorin Antikörper [DCN/6289] (A277635)

Monoklonal [DCN/6289] Maus Antikörper gegen Decorin für Flow Cytometry, IF, WB und IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Decorin Antibody [DCN/6289]
Beschreibung
Mouse monoclonal [DCN/6289] antibody to Decorin.
Spezifität
Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as Fibronectin and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGFβ and is a direct or indirect negative modulator of TGFβ synthesis. Inhibition of Decorin core protein gene expression by the combination of IFN-γ and TNFα may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. For immunostaining, pre-incubation with chondroitinase-SBC or testicular hyaluronidase may be required to expose the epitope.
Anwendungen
Flow Cytometry, IF, WB, IHC-P
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reaktivität
Human, Bovine, Canine, Chicken, Elk, Equine, Mouse, Porcine, Rabbit
Immunogen
Recombinant fragment corresponding to the C terminal core of bovine DCN.
Wirt
Mouse
Klonalität
Monoclonal
Klon
DCN/6289
Isotyp
IgG1
Leichte Ketten
lambda
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
200 µg/ml
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Decorin Antibody [DCN/6289] - BSA and Azide free (A278223).
Synonyme
Bone proteoglycan II, CSCD, DCN, DCN protein, Decorin proteoglycan, Dermatan sulphate proteoglycans II, DKFZp686J19238, DSPG 2, DSPG2, PG 40, PG II, PG S2, PG-S2, PG40, PGII, PGS 2, PGS2, PGS2_HUMAN, Proteoglycan core protein, SLRR1B, Small leucine rich protein 1B
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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