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Anti-FOXP3 Antikörper [3G3] (A252752)

Monoklonal [3G3] Maus Antikörper gegen FOXP3 für Flow Cytometry und IF.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
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Email
orders@antibodies.com

Empfohlene Produkte für Anti-FOXP3 Antikörper

Produktname
Anti-FOXP3 Antibody [3G3] - BSA and Azide free
Beschreibung
Mouse monoclonal [3G3] antibody to FOXP3.
Spezifität
This antibody recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion (amino acids 2-136) of the protein.The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Anwendungen
Flow Cytometry, IF
Verdünnungen
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reaktivität
Human, Monkey, Mouse
Immunogen
full-length his-tagged mouse FOXP3 protein.
Wirt
Mouse
Klonalität
Monoclonal
Klon
3G3
Isotyp
IgG1
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
47-55 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Allgemeine Hinweise
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-FOXP3 Antibody [3G3] (A249572).
Synonyme
AIID, DIETER, Forkhead box P3, Forkhead box protein P3, FOXP3delta7, FOXP3_HUMAN, Immune dysregulation polyendocrinopathy enteropathy X linked, Immunodeficiency polyendocrinopathy enteropathy X linked, IPEX, JM2, MGC141961, MGC141963, OTTHUMP00000025832, OTTHUMP00000025833, OTTHUMP00000226737, PIDX, Scurfin, XPID
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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