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Rekombinant Anti-Mast Cell Tryptase Antikörper [rTPSAB1/1963] (A316652)

$765

Monoklonal [rTPSAB1/1963] Maus Antikörper gegen Mast Cell Tryptase für IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Versandkosten
Vorlaufzeit
Lieferung in 4-6 Werktagen
Telefon
+1 (314) 370-6046
Mo bis Frei, 8am - 4pm AST
Email
orders@antibodies.com
Produktname
Anti-Mast Cell Tryptase Antibody [rTPSAB1/1963] - BSA and Azide free
Beschreibung
Recombinant mouse monoclonal [rTPSAB1/1963] antibody to Mast Cell Tryptase.
Spezifität
Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1). Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Tryptases are released into the extracellular environment and are resistant to all known endogenous proteinase inhibitors. This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis.
Anwendungen
IHC-P
Positivkontrolle
Human skin or tonsil.
Verdünnungen
IHC: 1-2 µg/ml
Reaktivität
Human
Immunogen
Recombinant human Tryptase protein fragment (around Amino Acids 100-250). The exact sequence is proprietary.
Wirt
Mouse
Klonalität
Monoclonal
Klon
rTPSAB1/1963
Isotyp
IgG1
Leichte Ketten
kappa
Konjugat

Unconjugated

Reinigung
Protein A/G chromatography.
Konzentration
1 mg/ml
Molekulargewicht
31-36 kDa
Produktform
Liquid
Formulierung
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Lagerung
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyme
alpha II, Lung tryptase, Mast cell alpha II tryptase, Mast cell beta I tryptase, Mast cell protease 7, Mast cell protease II, MCP 7, Pituitary tryptase, Skin tryptase, TPS 1, TPS1, TPS2, TPSAB1, TPSAB1 protein, TPSB1, Tryptase 1, Tryptase alpha 1, tryptase alpha I included, Tryptase alpha II, tryptase alpha II included, tryptase alpha included, tryptase alpha/beta 1, Tryptase beta 1, tryptase beta I included, Tryptase I, tryptase I included, Tryptase III, Tryptase skin
Haftungsausschluss
Dieses Produkt ist nur für Forschungszwecke bestimmt. Es ist nicht für diagnostische oder therapeutische Zwecke bestimmt.

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