Alpha 1 Acid Glycoprotein ist ein Gen, das durch das Symbol ORM1 kodiert wird. Andere Namen sind: Alpha-1-acid glycoprotein 1; AGP 1; Orosomucoid-1; OMD 1; ORM1; AGP1. Alpha 1 Acid Glycoprotein hat eine Masse von 23.51kDa und eine Aminosäurelänge von 201.
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Gen- und Proteininformationen
UniProt Zusammenfassung
Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.
Entrez Zusammenfassung
This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression.
Gewebespezifität
Expressed by the liver and secreted in plasma.
Sequenzähnlichkeiten
Belongs to the calycin superfamily. Lipocalin family.
Posttranslationale Modifikation
N-glycosylated. N-glycan heterogeneity at Asn-33: Hex5HexNAc4 (minor), Hex6HexNAc5 (major) and dHex1Hex6HexNAc5 (minor).