Eotaxin 3 ist ein Gen, das durch das Symbol CCL26 kodiert wird. Andere Namen sind: C-C motif chemokine 26; CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1; CCL26; SCYA26. Eotaxin 3 hat eine Masse von 10.65kDa und eine Aminosäurelänge von 94.
Wir bieten 3 Eotaxin 3 ELISA-Kits zum qualitativen oder quantitativen Nachweis von Eotaxin 3 von Human proben.
Gen- und Proteininformationen
UniProt Zusammenfassung
Chemoattractant for eosinophils and basophils (PubMed:10415065, PubMed:10488147). Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mobilization in eosinophils (PubMed:10415065, PubMed:10488147, PubMed:11425309).
Entrez Zusammenfassung
This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases.
Gewebespezifität
Ubiquitously expressed at low levels in various tissues including heart and ovary.
Sequenzähnlichkeiten
Belongs to the intercrine beta (chemokine CC) family.
