Substance P ist ein Gen, das durch das Symbol TAC1 kodiert wird. Es ist auch bekannt als: Protachykinin-1; PPT; TAC1; NKA; NKNA; TAC2. Substance P hat eine Masse von 15kDa und eine Aminosäurelänge von 129.
Wir bieten 7 Substance P ELISA-Kits zum qualitativen oder quantitativen Nachweis von Substance P von Human, Maus und Ratte proben.
Gen- und Proteininformationen
UniProt Zusammenfassung
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Entrez Zusammenfassung
This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene.
Sequenzähnlichkeiten
Belongs to the tachykinin family.
Posttranslationale Modifikation
The substance P form is cleaved at Pro-59 by the prolyl endopeptidase FAP (seprase) activity (in vitro).
