CNTN4 ist ein Gen, das durch das Symbol CNTN4 kodiert wird. Andere Namen sind: Contactin-4; Brain-derived immunoglobulin superfamily protein 2; BIG-2. CNTN4 hat eine Masse von 113.45kDa und eine Aminosäurelänge von 1026.
Wir bieten 4 antikörper gegen CNTN4, aufgewachsen in Kaninchen und Ziege, welche geeignet sind für WB, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis.
Entrez Zusammenfassung
This gene encodes a member of the contactin family of immunoglobulins. Contactins are axon-associated cell adhesion molecules that function in neuronal network formation and plasticity. The encoded protein is a glycosylphosphatidylinositol-anchored neuronal membrane protein that may play a role in the formation of axon connections in the developing nervous system. Deletion or mutation of this gene may play a role in 3p deletion syndrome and autism spectrum disorders. Alternative splicing results in multiple transcript variants.
Gewebespezifität
Mainly expressed in brain. Highly expressed in cerebellum and weakly expressed in corpus callosum, caudate nucleus, amygdala and spinal cord. Also expressed in testis, pancreas, thyroid, uterus, small intestine and kidney. Not expressed in skeletal muscle. Isoform 2 is weakly expressed in cerebral cortex.
Sequenzähnlichkeiten
Belongs to the immunoglobulin superfamily. Contactin family.
Zellort
Cell membrane. Secreted.
