FGF4 ist ein Gen, das durch das Symbol FGF4 kodiert wird. Andere Namen sind: Fibroblast growth factor 4; FGF-4; Heparin secretory-transforming protein 1; HST; Heparin-binding growth factor 4; HBGF-4; Transforming protein KS3; HSTF1; KS3. FGF4 hat eine Masse von 22.05kDa und eine Aminosäurelänge von 206.
Wir bieten 6 antikörper gegen FGF4, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC, ELISA and ICC/IF mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis.
Entrez Zusammenfassung
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
Sequenzähnlichkeiten
Belongs to the heparin-binding growth factors family.
