Histone H1 ist ein Gen, das durch das Symbol H1-0 kodiert wird. Im Allgemeinen auch bezeichnet als: Histone H1.0'(0); H1-0; H1F0; H1FV. Histone H1 hat eine Masse von 20.86kDa und eine Aminosäurelänge von 194.
Wir bieten 32 antikörper gegen Histone H1, aufgewachsen in Kaninchen und Maus, welche geeignet sind für WB, IHC, ELISA, ICC/IF, FC and IP mit Proben abgeleitet von Human, Maus, Ratte und Affe.
Gen- und Proteininformationen
UniProt Zusammenfassung
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The histones H1.0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
Entrez Zusammenfassung
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a replication-independent histone that is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The related mouse gene is expressed only in oocytes.
Sequenzähnlichkeiten
Belongs to the histone H1/H5 family.
Posttranslationale Modifikation
Phosphorylated on Ser-17 in RNA edited version.
Zellort
Nucleus. Chromosome.
The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes.
