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Anti-PRMT7 Antikörper

9 Products

PRMT7 ist ein Gen, das durch das Symbol PRMT7 kodiert wird. Im Allgemeinen auch bezeichnet als: Protein arginine N-methyltransferase 7; Histone-arginine N-methyltransferase [Myelin basic protein]-arginine N-methyltransferase KIAA1933. PRMT7 hat eine Masse von 78.46kDa, eine Aminosäurelänge von 692, und ist an Short stature, brachydactyly, intellectual developmental disability, and seizures beteiligt.

Wir bieten 9 antikörper gegen PRMT7, aufgewachsen in Kaninchen, Maus und Ziege, welche geeignet sind für WB, IHC, ELISA, ICC/IF, FC and IP mit Proben abgeleitet von Human, Maus und Ratte.

Gen- und Proteininformationen

UniProt Zusammenfassung
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
Entrez Zusammenfassung
This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients.
Rolle bei Krankheiten
Short stature, brachydactyly, intellectual developmental disability, and seizures: An autosomal recessive disease characterized by developmental delay, learning disabilities, mild mental retardation, delayed speech, and skeletal abnormalities. Skeletal features include short stature, brachydactyly, and short metacarpals and metatarsals.
Sequenzähnlichkeiten
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
Zellort
Cytoplasm > Cytosol. Nucleus.
Flow Cytometry - Anti-PRMT7 Antibody [PCRP-PRMT7-1A4] (A277755) - Antibodies.com
(6)
Produkt anzeigenMonospezifischer Antikörper
Flow Cytometry - Anti-PRMT7 Antibody [PCRP-PRMT7-1A4] - BSA and Azide free (A278343) - Antibodies.com
(6)
Produkt anzeigenMonospezifischer Antikörper
Flow Cytometry - Anti-PRMT7 Antibody [PCRP-PRMT7-1A7] - BSA and Azide free (A278344) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Flow Cytometry - Anti-PRMT7 Antibody [PCRP-PRMT7-1A7] (A277756) - Antibodies.com
(4)
Produkt anzeigenMonospezifischer Antikörper
Immunohistochemistry - Anti-PRMT7 Antibody (A92684) - Antibodies.com
(3)
Western Blot - Anti-PRMT7 Antibody [ARC2967] (A307461) - Antibodies.com
Western Blot - Anti-PRMT7 Antibody (A80946) - Antibodies.com
Western Blot - Anti-PRMT7 Antibody (A82785) - Antibodies.com
PRMT7 Antibody from Signalway Antibody (35889) - Antibodies.com

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