Prostate Specific Antigen ist ein Gen, das durch das Symbol KLK3 kodiert wird. Im Allgemeinen auch bezeichnet als: Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase; KLK3; APS. Prostate Specific Antigen hat eine Masse von 28.74kDa und eine Aminosäurelänge von 261.
Wir bieten 50 antikörper gegen Prostate Specific Antigen, aufgewachsen in Kaninchen, Maus, Ziege und Sheep, welche geeignet sind für WB, IHC, ELISA, ICC/IF, FC and IP mit Proben abgeleitet von Human, Maus und Katze.
Gen- und Proteininformationen
UniProt Zusammenfassung
Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Entrez Zusammenfassung
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
Sequenzähnlichkeiten
Belongs to the peptidase S1 family. Kallikrein subfamily.
