SLC10A1 ist ein Gen, das durch das Symbol SLC10A1 kodiert wird. Es ist auch bekannt als: Sodium/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na(+)/bile acid cotransporter; Na(+)/taurocholate transport protein; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; NTCP. SLC10A1 hat eine Masse von 38.12kDa und eine Aminosäurelänge von 349.
Wir bieten 3 antikörper gegen SLC10A1, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC and ELISA mit Proben abgeleitet von Human.
Gen- und Proteininformationen
UniProt Zusammenfassung
The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.
Entrez Zusammenfassung
The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis.
Sequenzähnlichkeiten
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
