SLC16A3 ist ein Gen, das durch das Symbol SLC16A3 kodiert wird. Es ist auch bekannt als: Monocarboxylate transporter 4; MCT 4; Solute carrier family 16 member 3; MCT4. SLC16A3 hat eine Masse von 49.47kDa und eine Aminosäurelänge von 465.
Wir bieten 2 antikörper gegen SLC16A3, aufgewachsen in Kaninchen, welche geeignet sind für WB, IHC and ELISA mit Proben abgeleitet von Human, Maus und Ratte.
Gen- und Proteininformationen
UniProt Zusammenfassung
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
Entrez Zusammenfassung
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998
Gewebespezifität
Highly expressed in skeletal muscle.
Sequenzähnlichkeiten
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
