Activin B ist ein Gen, das durch das Symbol INHBB kodiert wird. Andere Namen sind: Inhibin beta B chaineta-B chain; INHBB. Activin B hat eine Masse von 45.12kDa und eine Aminosäurelänge von 407.
Wir bieten 1 Activin Bproteine an
Gen- und Proteininformationen
UniProt Zusammenfassung
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Entrez Zusammenfassung
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. Polymorphisms near this gene are associated with pre-eclampsia in female human patients.
Sequenzähnlichkeiten
Belongs to the TGF-beta family.
