CD5 ist ein Gen, das durch das Symbol CD5 kodiert wird. Andere Namen sind: T-cell surface glycoprotein Lymphocyte antigen T1/Leu-1; LEU1. CD5 hat eine Masse von 54.58kDa und eine Aminosäurelänge von 495.
Wir bieten 2 CD5proteine an
Gen- und Proteininformationen
UniProt Zusammenfassung
May act as a receptor in regulating T-cell proliferation.
Entrez Zusammenfassung
This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Posttranslationale Modifikation
Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1.
