CXCL16 ist ein Gen, das durch das Symbol CXCL16 kodiert wird. Andere Namen sind: C-X-C motif chemokine 16; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Small-inducible cytokine B16; Transmembrane chemokine SCYB16; SRPSOX. CXCL16 hat eine Masse von 27.58kDa und eine Aminosäurelänge von 254.
Wir bieten 3 CXCL16proteine an
Gen- und Proteininformationen
UniProt Zusammenfassung
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
Gewebespezifität
Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
Sequenzähnlichkeiten
Belongs to the intercrine alpha (chemokine CxC) family.
Posttranslationale Modifikation
Glycosylated.
Zellort
Cell membrane. Secreted.
Also exists as a soluble form.
