CXCL5 ist ein Gen, das durch das Symbol CXCL5 kodiert wird. Andere Namen sind: C-X-C motif chemokine 5; ENA-78(1-78); Epithelial-derived neutrophil-activating protein 78; Neutrophil-activating peptide ENA-78; Small-inducible cytokine B5; ENA78; SCYB5. CXCL5 hat eine Masse von 11.97kDa und eine Aminosäurelänge von 114.
Wir bieten 7 CXCL5proteine an
Gen- und Proteininformationen
UniProt Zusammenfassung
Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.
Entrez Zusammenfassung
This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion.
Sequenzähnlichkeiten
Belongs to the intercrine alpha (chemokine CxC) family.
Posttranslationale Modifikation
N-terminal processed forms ENA-78(8-78) and ENA-78(9-78) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
