GM-CSF ist ein Gen, das durch das Symbol CSF2 kodiert wird. Im Allgemeinen auch bezeichnet als: Granulocyte-macrophage colony-stimulating factor; Colony-stimulating factor; CSF; Molgramostin; Sargramostim; CSF2; GMCSF. GM-CSF hat eine Masse von 16.3kDa und eine Aminosäurelänge von 144.
Wir bieten 4 GM-CSFproteine an
Gen- und Proteininformationen
UniProt Zusammenfassung
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Entrez Zusammenfassung
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.
Sequenzähnlichkeiten
Belongs to the GM-CSF family.
